Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 4/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14223271 | 0.82 | ADRA2B (0.49) | ADRA2BLOXL2MAPTGAATSHR | |
| SCHEMBL26037690 | 0.78 | ADRA2B (0.50) | ADRA2BMAPTGAATSHRMAPK1 | |
| SCHEMBL31175766 | 0.78 | ADRA2B (0.50) | ADRA2BMAPTGAATSHRMAPK1 | |
| SCHEMBL26037444 | 0.75 | GAA (0.44) | ADRA2BMAPTGAATSHRMAPK1 | |
| SCHEMBL7215312 | 0.74 | ADRA2B (0.47) | ADRA2BLOXL2MAPTGAATSHR | |
| SCHEMBL25302331 | 0.73 | PDE3B (0.47) | ADRA2B | |
| SCHEMBL30522527 | 0.73 | PDE3B (0.47) | ADRA2B | |
| SCHEMBL20085195 | 0.71 | TAAR1 (0.46) | MAPTGAATSHRMAPK1HTT | |
| SCHEMBL14945019 | 0.71 | TAAR1 (0.52) | LOXL2AOC1AOC3 | |
| SCHEMBL272096 | 0.70 | ALDH1A1 (0.56) | MAPTGAATSHRMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091697-A2 | MEDICAL IMAGING OF GLYCOGEN SYNTHASE KINASE-3 WITH A PET PROBE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-05-25 | — | — | WO | disclosed |