Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 17/20 | 0.40 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25584017 | 0.87 | GRIN2B (0.40) | GRIN2B | |
| SCHEMBL20049966 | 0.82 | GRIN2B (0.43) | GRIN2BGRIN1 | |
| SCHEMBL20049785 | 0.82 | GPBAR1 (0.39) | GRIN2BGRIN1 | |
| SCHEMBL20050012 | 0.81 | GRIN2B (0.42) | GRIN2BVRK1GRIN1 | |
| SCHEMBL25589007 | 0.78 | GRIN2B (0.43) | GRIN2BGRIN1 | |
| SCHEMBL25587614 | 0.77 | GRIN2B (0.42) | GRIN2BGRIN1 | |
| SCHEMBL25584224 | 0.77 | GRIN2B (0.40) | GRIN2BGRIN1 | |
| SCHEMBL25587627 | 0.77 | GRIN2B (0.46) | GRIN2BGRIN1 | |
| SCHEMBL25587827 | 0.76 | GRIN2B (0.42) | GRIN2BGRIN1 | |
| SCHEMBL25583605 | 0.76 | NOS3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |