SCHEMBL25587775

SCHEMBL25587775

CCCC(O)CN(CCCCCCN(CC(O)CCC)CC(O)CCC)CC(O)CCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PLA2G1B P04054 1/20 0.36
PLA2G2A P14555 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR84 Q9NQS5 4/20 0.32
GGPS1 O95749 3/20 0.32
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8641180 0.96 PLA2G1B (0.42) KDM4EMAPK1TDP1PLA2G1BPLA2G2A
SCHEMBL11211847 0.88 L3MBTL1 (0.34) L3MBTL1KDM4EMAPK1TDP1PLA2G1B
SCHEMBL17615502 0.87 KDM4E (0.35) L3MBTL1KDM4EMAPK1TDP1PLA2G1B
SCHEMBL11699005 0.87 KDM4E (0.45) KDM4EMAPK1TDP1PLA2G1BPLA2G2A
SCHEMBL17199810 0.87 GPR84 (0.47) L3MBTL1PLA2G1BPLA2G2AGPR84
SCHEMBL3536738 0.86 KDM4E (0.47) L3MBTL1KDM4EMAPK1TDP1PLA2G1B
SCHEMBL12469261 0.86 FFAR1 (0.43) MEN1KMT2A
SCHEMBL17615501 0.85 DNM1 (0.38) L3MBTL1KDM4EMAPK1TDP1MEN1
SCHEMBL17615498 0.84 KDM4E (0.34) L3MBTL1KDM4EMAPK1TDP1MEN1
SCHEMBL1354800 0.83 L3MBTL1 (0.36) L3MBTL1KDM4EMAPK1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159581-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS SYNOVO GMBH (DE) 2023-05-25 US disclosed
US-20230131943-A1 ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS BURNET MICHEAL W (DE) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131943-A1 ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS CTSA, GAA, SLC7A5 L3MBTL1 1536/4885KDM4E 3394/4885MAPK1 3989/4885
US-20230159581-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS CTSA, ALOX15, ALOX5 L3MBTL1 1562/4885KDM4E 3648/4885MAPK1 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.