Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 4/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 4/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23776750 | 0.88 | HRH3 (0.56) | HRH3SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL24707744 | 0.80 | CHRNB2 (0.50) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25094644 | 0.76 | CHRNB2 (0.41) | HRH3SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL25584716 | 0.76 | HRH3 (0.48) | HRH3SMN1; SMN2KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL18051840 | 0.75 | HSD11B1 (0.60) | SMN1; SMN2NPC1RAB9AKMT2ACHRNB2 | |
| SCHEMBL19504480 | 0.75 | HPGD (0.41) | HRH3SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL21016656 | 0.74 | HRH3 (0.34) | HRH3 | |
| SCHEMBL25583774 | 0.74 | HRH3 (0.34) | HRH3 | |
| SCHEMBL26170649 | 0.74 | HRH3 (0.55) | HRH3SMN1; SMN2CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL24342185 | 0.74 | CHRNB2 (0.44) | SMN1; SMN2NPC1RAB9AKMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167131-A1 | HETEROCYCLIC PAD4 INHIBITORS | PADI4, PADI2, PADI6 | HRH3 1991/4885SMN1; SMN2 1715/4885NPC1 3595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.