Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 6/20 | 0.60 |
| ▸ | CCNK | O75909 | 6/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.60 |
| ▸ | CDK2 | P24941 | 6/20 | 0.60 |
| ▸ | CDK9 | P50750 | 6/20 | 0.60 |
| ▸ | CDK12 | Q9NYV4 | 6/20 | 0.60 |
| ▸ | CDK7 | P50613 | 7/20 | 0.50 |
| ▸ | CCNH | P51946 | 7/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 5/20 | 0.50 |
| ▸ | CLK1 | P49759 | 8/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25598658 | 0.87 | CCNT1 (0.60) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL24839463 | 0.76 | CCNK (1.00) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL4925137 | 0.71 | DYRK1A (0.57) | CDK2CLK1CDK5CDK5R1 | |
| SCHEMBL25029052 | 0.71 | MEN1 (0.44) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL24839617 | 0.67 | CLK1 (0.49) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30480922 | 0.65 | CLK1 (0.76) | CLK1CDK5CDK5R1MEN1KMT2A | |
| SCHEMBL23059871 | 0.64 | CCNT1 (0.57) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL31049314 | 0.64 | NR3C1 (0.43) | CCNT1CCNKCCNE1CDK2CDK9 | |
| SCHEMBL30268103 | 0.64 | ADORA1 (0.53) | GAA | |
| SCHEMBL29364536 | 0.64 | ADRB3 (0.37) | CCNT1CCNKCCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484871-B1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF CYCLIN DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |