Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CTSC | P53634 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681855 | 1.00 | BRPF1 (0.39) | BRPF1EGFRCSF1RMAPTPOLB | |
| SCHEMBL25599780 | 0.94 | IRAK4 (0.41) | BRPF1EGFRCSF1RMAPTCTSC | |
| SCHEMBL25682533 | 0.89 | CCNA2 (0.39) | CSF1RMAPTCTSCGAAUCHL3 | |
| SCHEMBL25599817 | 0.89 | UCHL3 (0.37) | EGFRCSF1RCTSCUCHL3 | |
| SCHEMBL25681883 | 0.89 | BRPF1 (0.39) | BRPF1EGFRMAPTPOLBCTSC | |
| SCHEMBL25599216 | 0.89 | CCNA2 (0.39) | CSF1RMAPTCTSCGAAUCHL3 | |
| SCHEMBL25599631 | 0.89 | CDK7 (0.38) | EGFRCSF1RCTSCUCHL3 | |
| SCHEMBL25599672 | 0.89 | CCNA2 (0.38) | EGFRCSF1RUCHL3 | |
| SCHEMBL25599189 | 0.89 | UCHL3 (0.36) | EGFRCSF1RCTSCUCHL3 | |
| SCHEMBL25599771 | 0.88 | CCNA2 (0.37) | EGFRUCHL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |