Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681855 | 0.94 | BRPF1 (0.39) | EGFRMAPTCTSBCTSCCSF1R | |
| SCHEMBL25599717 | 0.94 | BRPF1 (0.39) | EGFRMAPTCTSBCTSCCSF1R | |
| SCHEMBL25599743 | 0.88 | BTK (0.40) | EGFRADORA2AADORA1CCNKCDK12 | |
| SCHEMBL25599216 | 0.85 | CCNA2 (0.39) | MAPTCTSBCTSCCSF1RCCNK | |
| SCHEMBL25599631 | 0.85 | CDK7 (0.38) | EGFRCTSCCSF1RCCNKCDK12 | |
| SCHEMBL25682533 | 0.85 | CCNA2 (0.39) | MAPTCTSBCTSCCSF1RCCNK | |
| SCHEMBL25599817 | 0.85 | UCHL3 (0.37) | EGFRCTSCCSF1RFGFR4CCNK | |
| SCHEMBL25599189 | 0.84 | UCHL3 (0.36) | EGFRCTSCCSF1RFGFR4CCNK | |
| SCHEMBL25599672 | 0.84 | CCNA2 (0.38) | EGFRCSF1RCCNKCDK12 | |
| SCHEMBL25599623 | 0.84 | FGFR4 (0.36) | EGFRCTSCCSF1RFGFR4CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023102184-A1 | BICYCLIC AMINE COMPOUNDS AS CDK12 INHIBITORS | INCYTE CORPORATION (US) | 2023-06-08 | — | — | WO | disclosed |