Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRAP1 | Q12931 | 3/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970490 | 0.88 | TRAP1 (0.33) | TRAP1HSP90B1MEN1GAAKMT2A | |
| SCHEMBL30970491 | 0.83 | KCNA1 (0.36) | AVPR1BHTTNPSR1LMNA | |
| SCHEMBL30970488 | 0.80 | HSP90AA1 (0.40) | MEN1GAAKMT2AAVPR1BPOLB | |
| SCHEMBL30301748 | 0.78 | TRAP1 (0.35) | TRAP1HSP90B1MEN1KMT2ASLC6A9 | |
| SCHEMBL30301766 | 0.78 | TRAP1 (0.37) | TRAP1HSP90B1MEN1KMT2ASLC6A9 | |
| SCHEMBL30970485 | 0.77 | HSP90AA1 (0.33) | TRAP1HSP90B1MEN1GAAKMT2A | |
| SCHEMBL30970486 | 0.77 | HSP90AA1 (0.33) | TRAP1HSP90B1MEN1GAAKMT2A | |
| SCHEMBL31282296 | 0.76 | TRAP1 (0.42) | TRAP1HSP90B1 | |
| SCHEMBL30970487 | 0.75 | CCNA2 (0.34) | — | |
| SCHEMBL30970483 | 0.75 | CCNA2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317949-A | Isoindolines as PMS2 inhibitors | 奈奥芬莱有限公司 | 2024-07-09 | — | — | CN | disclosed |