Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25615033 | 0.86 | ADK (0.30) | — | |
| SCHEMBL25614650 | 0.81 | HTT (0.42) | HTTMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL25614598 | 0.75 | KDM4E (0.40) | MAPTKDM4EALDH1A1GAATDO2 | |
| SCHEMBL30811694 | 0.74 | GRM5 (0.31) | GRM5 | |
| SCHEMBL25614363 | 0.74 | CYP2A6 (0.41) | KDM4EALDH1A1SMN1; SMN2CYP2A6 | |
| SCHEMBL14299558 | 0.72 | CYP2E1 (0.48) | CYP2A6 | |
| SCHEMBL25614665 | 0.72 | RAB9A (0.43) | HTTMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL2690822 | 0.72 | ELOVL1 (0.46) | HTTMAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL22531723 | 0.72 | GRM5 (0.38) | GRM5CYP2A6 | |
| SCHEMBL30811735 | 0.71 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |