Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17640922 | 0.82 | RAB9A (0.48) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL25615031 | 0.79 | CHRNB2 (0.38) | HTTCHRNB2CHRNA4CYP11B2CYP2A6 | |
| SCHEMBL2690822 | 0.79 | ELOVL1 (0.46) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL30474527 | 0.77 | MAPT (0.50) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL5535694 | 0.77 | MAPT (0.50) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL5544146 | 0.76 | HTT (0.56) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL25614650 | 0.76 | HTT (0.42) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL15935029 | 0.76 | CYP11B2 (0.42) | RAB9AMAPTKDM4EALDH1A1GAA | |
| SCHEMBL13274537 | 0.72 | CHRNB2 (0.33) | ALDH1A1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL25614666 | 0.72 | HTT (0.39) | RAB9AMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |