Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25615020 | 0.81 | CHRNB4 (0.39) | CHRNA3CHRNB4CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL25614666 | 0.81 | HTT (0.39) | HTTRAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL25614665 | 0.76 | RAB9A (0.43) | HTTRAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL2690822 | 0.76 | ELOVL1 (0.46) | HTTRAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL25615106 | 0.73 | CHRNA3 (0.42) | HTTMAPTKDM4EALDH1A1CHRNA3 | |
| SCHEMBL25615105 | 0.72 | CHRNA3 (0.39) | CHRNA3CHRNB4CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL25615104 | 0.72 | CHRNA3 (0.39) | CHRNA3CHRNB4CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL15935029 | 0.72 | CYP11B2 (0.42) | HTTRAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL30811674 | 0.71 | KDM4E (0.44) | MAPTKDM4EALDH1A1GAACHRNA3 | |
| SCHEMBL25614588 | 0.71 | KDM4E (0.44) | MAPTKDM4EALDH1A1GAACHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104209-A1 | METTL3 INHIBITOR COMPOUND | 上海昂阔医药有限公司 | 2023-06-15 | — | — | WO | disclosed |