Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.39 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | TEK | Q02763 | 3/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029089 | 0.71 | MET (0.45) | METAURKAKDRTEKAURKB | |
| SCHEMBL17732799 | 0.71 | HTR1A (0.44) | METAURKAKDRTEKAURKB | |
| SCHEMBL28771093 | 0.69 | MET (0.54) | METAURKAKDRTEKAURKB | |
| SCHEMBL8145365 | 0.66 | HTR1A (0.61) | METAURKAKDRTEKAURKB | |
| SCHEMBL19204448 | 0.64 | PDGFRA (0.48) | METAURKAKDRTEKAURKB | |
| SCHEMBL24028704 | 0.62 | KDR (0.45) | METAURKAKDRTEKAURKB | |
| SCHEMBL29952206 | 0.61 | HTR1A (0.55) | METAURKAKDRTEKAURKB | |
| SCHEMBL29878429 | 0.60 | MET (0.54) | METAURKAKDRTEKAURKB | |
| SCHEMBL2700581 | 0.60 | MET (0.54) | METAURKAKDRTEKAURKB | |
| SCHEMBL13443841 | 0.60 | HTR1A (0.57) | METHTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183188-A1 | ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183188-A1 | ENPP1 MODULATORS AND USES THEREOF | ENPP1, ENPP2, ENPP3 | MET 4868/4885AURKA 3548/4885KDR 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.