Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 6/20 | 0.59 |
| ▸ | MAOB | P27338 | 6/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 5/20 | 0.47 |
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216492 | 0.88 | SLC6A11 (0.78) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL21580251 | 0.76 | SLC6A11 (0.61) | SLC6A11PGRKCNH2 | |
| SCHEMBL30512416 | 0.76 | SLC6A11 (0.61) | SLC6A11PGRKCNH2 | |
| SCHEMBL2789935 | 0.75 | MAOA (1.00) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL27554974 | 0.73 | SLC6A11 (0.58) | SLC6A11PGRALDH1A1KCNH2CASP3 | |
| SCHEMBL11213472 | 0.72 | PDE3B (1.00) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL29956338 | 0.72 | PGR (0.56) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL25367285 | 0.71 | MAOA (0.74) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL30588923 | 0.71 | MAOA (0.74) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL2787830 | 0.71 | MAOA (0.73) | SLC6A11MAOAMAOBPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |