Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | PRF1 | P14222 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 5/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329893 | 0.74 | MAOA (0.68) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL2020897 | 0.73 | PRF1 (0.65) | PGRPRF1MAPTCYP2E1CYP3A4 | |
| SCHEMBL2557384 | 0.72 | MAOA (0.64) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL2562512 | 0.72 | SLC6A11 (1.00) | PGRSLC6A11MAOAMAOBPDE3B | |
| SCHEMBL2039248 | 0.71 | PRF1 (0.67) | PGRPRF1MAPT | |
| SCHEMBL2561538 | 0.71 | MAOA (0.67) | SLC6A11MAOAMAOBPDE3BPDE3A | |
| SCHEMBL2019635 | 0.70 | PRF1 (0.68) | PGRPRF1MAPT | |
| SCHEMBL9116280 | 0.70 | MAOA (0.65) | MAOAMAOBPDE3BPDE3ATGM2 | |
| SCHEMBL22694901 | 0.69 | PRF1 (0.51) | PGRPRF1MAPTALDH1A1CYP2E1 | |
| SCHEMBL13706014 | 0.69 | PGR (0.53) | PGRPRF1MAPTALDH1A1CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |