SCHEMBL25627552

SCHEMBL25627552

CC(=O)NCC(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 9/20 0.51
OPRM1 P35372 8/20 0.51
OPRK1 P41145 2/20 0.51
ACE P12821 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25627547 0.91 ACE (0.48) OPRD1OPRM1OPRK1ACE
SCHEMBL25626461 0.88 ACE (0.48) OPRM1ACE
SCHEMBL12060305 0.88 CTSL (0.37)
SCHEMBL11765581 0.86 REN (0.54) OPRM1ACE
SCHEMBL11759100 0.86 REN (0.54) OPRM1ACE
Hydrochloric Acid SCHEMBL11764160 0.85 REN (0.53) OPRM1ACE
SCHEMBL1660937 0.85 APC (0.52)
SCHEMBL1661198 0.84 CTSL (0.57) ACE
SCHEMBL18556712 0.83 KISS1R (0.55) OPRD1OPRM1
SCHEMBL25627202 0.83 OPRD1 (0.57) OPRD1OPRM1OPRK1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023106897-A1 NOVEL PEPTIDE DERIVATIVE DERIVED FROM ADIPONECTIN AND USE THEREOF 서울대학교병원 2023-06-15 WO disclosed