Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19619217 | 0.79 | IDO1 (0.32) | ADRB1ADRB2PTGS2 | |
| SCHEMBL12150218 | 0.77 | ADRB1 (0.31) | ADRB1 | |
| SCHEMBL25628192 | 0.74 | KRAS (0.32) | ADRB1ADRB2 | |
| SCHEMBL7042571 | 0.71 | NOS3 (0.41) | PTGS2 | |
| SCHEMBL397098 | 0.71 | NOS3 (0.41) | PTGS2 | |
| SCHEMBL25628423 | 0.70 | SOS1 (0.51) | — | |
| SCHEMBL10554547 | 0.69 | MAOA (0.46) | ADRB1ADRB2 | |
| SCHEMBL25628203 | 0.68 | SOS1 (0.39) | ADRB1ADRB2 | |
| SCHEMBL28716332 | 0.68 | ADRB2 (0.36) | ADRB2PTGS2 | |
| SCHEMBL21779670 | 0.67 | GABRA1 (0.34) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |