Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195827 | 0.81 | LMNA (0.49) | ALDH1A1KMT2APOLBKDM4ELMNA | |
| SCHEMBL14615359 | 0.74 | HRH3 (0.50) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL19832548 | 0.69 | SIGMAR1 (0.61) | ALDH1A1MEN1KMT2APOLBKDM4E | |
| SCHEMBL10823156 | 0.67 | BACE1 (0.38) | PPARGLMNA | |
| SCHEMBL21540222 | 0.66 | PRMT6 (0.50) | ALDH1A1POLBKDM4EHRH3SMN1; SMN2 | |
| SCHEMBL9734907 | 0.66 | CNR1 (0.48) | L3MBTL1 | |
| SCHEMBL18052718 | 0.65 | CHKA (0.57) | ALDH1A1KDM4ELMNA | |
| SCHEMBL24250764 | 0.65 | KDM4E (0.57) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL11791277 | 0.64 | TRPA1 (0.41) | ALDH1A1L3MBTL1PPARGSMN1; SMN2LMNA | |
| SCHEMBL21400966 | 0.64 | HRH3 (0.50) | ALDH1A1L3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |