Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630561 | 0.86 | KIT (0.41) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25725210 | 0.82 | CYP1A2 (0.41) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25630530 | 0.76 | PTK2 (0.50) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25630734 | 0.75 | CYP1A2 (0.42) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25725161 | 0.72 | AURKA (0.47) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25630640 | 0.72 | HTT (0.37) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25633293 | 0.71 | HTT (0.52) | HTTMEN1ALDH1A1KDM4EKMT2A | |
| SCHEMBL25229702 | 0.70 | AKT1 (0.44) | JAK3KITAKT1 | |
| SCHEMBL31501711 | 0.69 | HTT (0.44) | HTTMEN1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL25227852 | 0.69 | HTT (0.44) | HTTMEN1CYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |