Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640475 | 0.88 | CHRNB2 (0.44) | LMNAALDH1A1MAPK1KMT2ATRPV6 | |
| SCHEMBL25479105 | 0.87 | JAK2 (0.35) | GSK3BLTA4HKCNJ1GRIN1GRIN2B | |
| SCHEMBL25640513 | 0.87 | TACR1 (0.40) | LMNALTA4HALDH1A1GRIN1GRIN2B | |
| SCHEMBL25478882 | 0.87 | LTA4H (0.39) | LTA4HCYP1A2CYP3A4KCNJ1ALDH1A1 | |
| SCHEMBL25640507 | 0.87 | HRH3 (0.40) | CCR2LTA4HCYP1A2CYP3A4MEN1 | |
| SCHEMBL25640471 | 0.86 | TACR1 (0.44) | CYP3A4 | |
| SCHEMBL25640511 | 0.85 | MLNR (0.44) | LMNAALDH1A1SIGMAR1KDM4E | |
| SCHEMBL23943756 | 0.84 | SIGMAR1 (0.47) | LTA4HMEN1KMT2ASIGMAR1 | |
| SCHEMBL25190429 | 0.84 | SIGMAR1 (0.47) | LTA4HMEN1KMT2ASIGMAR1 | |
| SCHEMBL25640515 | 0.84 | ALDH1A1 (0.42) | LTA4HALDH1A1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |