Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640474 | 0.88 | PKM (0.41) | ALDH1A1KDM4EKMT2ATRPV6LMNA | |
| SCHEMBL25354748 | 0.84 | DRD4 (0.43) | CHRNB2CHRNA4ALDH1A1KDM4ETDP1 | |
| SCHEMBL25354750 | 0.84 | DRD4 (0.43) | CHRNB2CHRNA4ALDH1A1KDM4ETDP1 | |
| SCHEMBL31677627 | 0.83 | KCNJ1 (0.39) | KDM4ETDP1MAPK1 | |
| SCHEMBL25640470 | 0.83 | KCNJ1 (0.39) | KDM4ETDP1MAPK1 | |
| SCHEMBL25640507 | 0.82 | HRH3 (0.40) | TDP1KMT2A | |
| SCHEMBL25478882 | 0.82 | LTA4H (0.39) | ALDH1A1KDM4E | |
| SCHEMBL25640513 | 0.82 | TACR1 (0.40) | ALDH1A1DRD2DRD4HTTLMNA | |
| SCHEMBL25221452 | 0.81 | TRPV6 (0.44) | TRPV6 | |
| SCHEMBL30414542 | 0.81 | TRPV6 (0.44) | TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |