Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 11/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31677627 | 1.00 | KCNJ1 (0.39) | KCNJ1TDP1MAPK1L3MBTL1TLR9 | |
| SCHEMBL25640472 | 0.89 | KMT2A (0.41) | KCNJ1L3MBTL1TLR9TLR8TLR7 | |
| SCHEMBL25640474 | 0.83 | PKM (0.41) | KCNJ1MAPK1KDM4E | |
| SCHEMBL25640475 | 0.83 | CHRNB2 (0.44) | TDP1MAPK1KDM4E | |
| SCHEMBL25478882 | 0.82 | LTA4H (0.39) | KCNJ1KDM4E | |
| SCHEMBL25640513 | 0.82 | TACR1 (0.40) | — | |
| SCHEMBL25640507 | 0.82 | HRH3 (0.40) | TDP1 | |
| SCHEMBL25640471 | 0.81 | TACR1 (0.44) | — | |
| SCHEMBL25221452 | 0.79 | TRPV6 (0.44) | KCNJ1TLR9TLR8TLR7 | |
| SCHEMBL30414542 | 0.79 | TRPV6 (0.44) | KCNJ1TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |