Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23944111 | 0.83 | KCNJ1 (0.38) | LMNAL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL25264679 | 0.83 | KCNJ1 (0.38) | LMNAL3MBTL1ALDH1A1POLBKDM4E | |
| SCHEMBL25640474 | 0.83 | PKM (0.41) | LMNASIGMAR1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL25640475 | 0.80 | CHRNB2 (0.44) | LMNAKMT2AALDH1A1KDM4ETRPV6 | |
| SCHEMBL25479105 | 0.80 | JAK2 (0.35) | SIGMAR1 | |
| SCHEMBL25478882 | 0.79 | LTA4H (0.39) | SIGMAR1CYP1A2CYP2C19ALDH1A1POLB | |
| SCHEMBL25640513 | 0.79 | TACR1 (0.40) | LMNASIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25640507 | 0.79 | HRH3 (0.40) | SIGMAR1CYP1A2CYP2C19KMT2A | |
| SCHEMBL25640471 | 0.78 | TACR1 (0.44) | — | |
| SCHEMBL25640473 | 0.78 | TACR1 (0.45) | CYP1A2CYP2C19KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |