Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533925 | 0.79 | MAPT (0.46) | HTTALDH1A1NPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL5532547 | 0.76 | MAPT (0.45) | HTTALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL5535769 | 0.75 | GABRP (0.42) | HTTALDH1A1SMN1; SMN2MAPK1POLB | |
| SCHEMBL8805923 | 0.75 | ROCK2 (0.45) | HTTALDH1A1NPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL5526963 | 0.73 | ALOX5 (0.42) | HTTALDH1A1NPSR1SMN1; SMN2MAPK1 | |
| SCHEMBL8806089 | 0.71 | CNR1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL8805163 | 0.69 | EGFR (0.53) | HTTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8805594 | 0.69 | ROCK2 (0.48) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8805331 | 0.69 | NPY5R (0.42) | ALDH1A1NPSR1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7416262 | 0.68 | ACHE (0.44) | HTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011133862-A1 | METHODS AND COMPOSITIONS FOR PROMOTING MYELINATION | OREGON HEALTH AND SCIENCE UNIVERSITY (US) | 2011-10-27 | — | — | WO | claimed |
| WO-2011133862-A1 | METHODS AND COMPOSITIONS FOR PROMOTING MYELINATION | OREGON HEALTH AND SCIENCE UNIVERSITY (US) | 2011-10-27 | — | — | WO | disclosed |