Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535769 | 0.87 | GABRP (0.42) | MAPTPOLBSAE1UBA2MEN1 | |
| SCHEMBL5532547 | 0.87 | MAPT (0.45) | MAPTPOLBSAE1UBA2MEN1 | |
| SCHEMBL7639782 | 0.85 | JAK2 (0.41) | MAPTPOLBSAE1UBA2ALOX5 | |
| SCHEMBL4960029 | 0.84 | PDE4A (0.56) | MAPTPOLBSAE1UBA2ALOX5 | |
| SCHEMBL5526963 | 0.84 | ALOX5 (0.42) | MAPTPOLBSAE1UBA2ALOX5 | |
| SCHEMBL2564222 | 0.79 | HTT (0.44) | MAPTPOLBMEN1KMT2ATAAR1 | |
| SCHEMBL5535174 | 0.79 | MAPT (0.46) | MAPTPOLBSAE1UBA2ALOX5 | |
| SCHEMBL5534063 | 0.78 | RXFP1 (0.43) | MAPTALOX5MEN1KMT2ATAAR1 | |
| SCHEMBL4029345 | 0.78 | POLB (0.45) | MAPTPOLBMEN1KMT2ATAAR1 | |
| SCHEMBL3824082 | 0.76 | TUBB4A (0.53) | MAPTPOLBALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2007-07-25 | — | — | EP | claimed |
| WO-2006052712-A1 | NANOPARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INTERNATIONAL INC. (US) | 2006-05-18 | — | — | WO | claimed |