SCHEMBL25647102

SCHEMBL25647102

Cc1cc(C)c(/N=C(\c2ccccc2)c2cccc(/C(=N/c3c(C)cc(C)cc3C(C)C)c3ccccc3)n2)c(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 2/20 0.32
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21078305 0.91 RAB9A (0.39) KMT2AMEN1RAB9ALMNAKDM4E
SCHEMBL23982608 0.90 RAB9A (0.38) KMT2AMEN1RAB9ALMNAKDM4E
SCHEMBL5590401 0.87 GABRA1 (0.37) KMT2AMEN1LMNAGABRA1GABRB1
SCHEMBL25940731 0.86 MEN1 (0.36) KMT2AMEN1RAB9ALMNAKDM4E
SCHEMBL5588856 0.86 GABRA1 (0.36) KMT2AMEN1LMNAGABRA1GABRB1
SCHEMBL25647100 0.84 LMNA (0.34) LMNA
SCHEMBL23982592 0.83 KMT2A (0.35) KMT2AMEN1RAB9ALMNAKDM4E
SCHEMBL25647103 0.83 LMNA (0.35) KMT2ARAB9ALMNAGABRA1GABRB1
SCHEMBL25940738 0.82 MEN1 (0.34) KMT2AMEN1RAB9ALMNAKDM4E
SCHEMBL14280811 0.82 ALDH1A1 (0.39) KMT2AMEN1LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11738334-B2 Supported catalyst systems and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-29 US disclosed
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-08 US disclosed
US-20230174757-A1 Linear Low Density Polyethylene for Film Applications EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof IDO2, SLC40A1, IDO1 KMT2A 1685/4885MEN1 1112/4885RAB9A 4241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.