SCHEMBL2565196

SCHEMBL2565196

C[Si](C)(C)c1ccccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PNMT P11086 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HSD11B1 P28845 1/20 0.37
CYP2A6 P11509 4/20 0.35
CYP1A2 P05177 3/20 0.35
AHR P35869 1/20 0.34
NOTUM Q6P988 1/20 0.34
IDO1 P14902 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31193363 1.00 TSHR (0.47) TSHRLMNAHPGDNPC1TP53
SCHEMBL5375946 0.81 TSHR (0.45) TSHRLMNAHPGDNPC1TP53
SCHEMBL1798315 0.81 TSHR (0.45) TSHRLMNAHPGDNPC1TP53
SCHEMBL9571098 0.79 TSHR (0.42) TSHRLMNAPNMTALDH1A1CYP2A6
SCHEMBL29726936 0.78 IDO1 (0.41) TSHRLMNANPC1RAB9ASMN1; SMN2
SCHEMBL1880902 0.78 IDO1 (0.41) TSHRLMNANPC1RAB9ASMN1; SMN2
SCHEMBL29264599 0.75 TSHR (0.39) TSHRLMNAHPGDNPC1TP53
SCHEMBL7223546 0.75 ALDH1A1 (0.41) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL10356447 0.75 CFD (0.35) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL1225074 0.74 TSHR (0.50) TSHRLMNAHPGDNPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12306373-B2 Low melting point ionic liquids for infra-red liquid lens design CORNING INCORPORATED (US) 2025-05-20 US claimed
US-12306373-B2 Low melting point ionic liquids for infra-red liquid lens design CORNING INCORPORATED (US) 2025-05-20 US disclosed
EP-3769141-B1 TRANSMISSION RECOVERY AGENTS FOR LIQUID LENS FORMULATIONS CORNING INC (US) 2025-01-08 EP disclosed
US-20230307651-A1 CARBONACEOUS MATERIAL DISPERSION FOR ALL-SOLID LITHIUM ION RECHARGEABLE BATTERY, AND SLURRY FOR ELECTRODE OF ALL-SOLID LITHIUM ION RECHARGEABLE BATTERY Refine Holdings Co., Ltd. (JP) 2023-09-28 US disclosed
CN-116420244-A Carbonaceous material dispersion for all-solid lithium ion secondary battery and electrode slurry for all-solid lithium ion secondary battery 瑞环控股有限公司 2023-07-11 CN disclosed
US-11691364-B2 Methods of manufacturing liquid lenses CORNING INCORPORATED (US) 2023-07-04 US disclosed
US-20220099862-A1 LOW MELTING POINT IONIC LIQUIDS FOR INFRA-RED LIQUID LENS DESIGN LG INNOTEK CO., LTD. (KR) 2022-03-31 US disclosed
EP-3918383-A1 LOW MELTING POINT IONIC LIQUIDS FOR INFRA-RED LIQUID LENS DESIGN Corning Incorporated (US) 2021-12-08 EP disclosed
CN-113661161-A Low-melting-point ionic liquid for infrared liquid lens design 康宁股份有限公司 2021-11-16 CN disclosed
US-20210223442-A1 NEGATIVE OPTICAL POWER LIQUID LENS CORNING INCORPORATED 2021-07-22 US disclosed
EP-1816491-A1 Electrowetting device Varioptic (FR) 2007-08-08 EP disclosed
US-20070177276-A1 Optical electrowetting device VARIOPTIC S.A. 2007-08-02 US disclosed
US-20070179201-A1 Use of bromine anions in an optical electrowetting device VARIOPTIC S.A. 2007-08-02 US disclosed
US-20070179200-A1 Multi-phase liquid composition and optical electrowetting device that incorporates the same VARIOPTIC S.A. 2007-08-02 US disclosed
US-5027157-A Developing device provided with electrodes for inducing a traveling wave on the developing material MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-4971880-A MULTILAYER TONERS, DEVELOPERS, FOR ELECTROSTATIC LATENT IMAGES, CORES AND HALOGENATED CARBON PARTICLES MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1990-11-20 US disclosed
US-4867541-A FILM FORMED BY PLASMA POLYMERIZATION OF PHTHALOCYANINE COMPOUND MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-09-19 US disclosed
US-4828369-A ELECTROLYTES, PLASMA POLYMERIZATION OF HYDROCARBON, ALKALI METAL /COMPOUND/, ELECTRONEGATIVITY MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-05-09 US disclosed
US-4801515-A Photosensitive member having an overcoat layer MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1989-01-31 US disclosed
EP-0252442-A2 Photosensitive member having an overcoat layer Minolta Camera Kabushiki Kaisha (JP) 1988-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12306373-B2 Low melting point ionic liquids for infra-red liquid lens design IK, CRYZ, CRYAA TSHR 2645/4885LMNA 124/4885HPGD 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.