SCHEMBL2565596

SCHEMBL2565596

CCCCC/C=C\C/C=C\CCCCCC1OC1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
ALDH1A1 P00352 5/20 0.55
PPARG P37231 5/20 0.55
F7 P08709 4/20 0.55
F3 P13726 4/20 0.55
PPARD Q03181 4/20 0.55
PPARA Q07869 4/20 0.55
KDM4E B2RXH2 4/20 0.55
FFAR1 O14842 3/20 0.55
FABP3 P05413 3/20 0.55
LMNA P02545 2/20 0.55
CYP3A4 P08684 2/20 0.55
CYP19A1 P11511 2/20 0.55
FABP4 P15090 2/20 0.55
HPGD P15428 2/20 0.55
ALOX15 P16050 2/20 0.55
PTGS1 P23219 2/20 0.55
AKR1C3 P42330 2/20 0.55
NR4A2 P43354 2/20 0.55
HSD17B10 Q99714 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228889 0.95 TERT (0.51) MAPTPPARGF7F3PPARD
SCHEMBL27998592 0.95 TERT (0.51) MAPTPPARGF7F3PPARD
SCHEMBL2228887 0.95 TERT (0.51) MAPTPPARGF7F3PPARD
SCHEMBL16322869 0.95 TERT (0.51) MAPTPPARGF7F3PPARD
SCHEMBL27998317 0.94 TERT (0.50) MAPTPPARGF7F3PPARD
SCHEMBL27998318 0.94 TERT (0.50) MAPTPPARGF7F3PPARD
Water SCHEMBL27998596 0.92 TERT (0.49) MAPTPPARGF7F3PPARD
SCHEMBL19439425 0.91 ALDH1A1 (0.55) MAPTALDH1A1PPARGF7F3
SCHEMBL3503266 0.89 FASN (0.54) MAPTPPARGKDM4ELMNAFABP4
SCHEMBL2507774 0.89 ALOX5 (0.61) MAPTALDH1A1PPARGF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106349-B Full-bio-based hyperbranched photocuring prepolymer and preparation method and application thereof 华南农业大学 2023-01-17 CN claimed
CN-114890968-A Green and environment-friendly plasticizer and preparation method thereof 电子科技大学 2022-08-12 CN claimed
CN-109096984-B Water-resistant animal bone glue adhesive 常州五荣化工有限公司 2021-08-27 CN claimed
CN-107151419-B A kind of high tenacity cold mixing bituminous epoxy binder and preparation method thereof 河海大学 2019-11-15 CN claimed
CN-110396176-A Vegetable oil-based epoxy acrylate resin and preparation method and application thereof INST CHEMICAL IND FOREST PRODUCTS CAF 2019-11-01 CN claimed
CN-109096984-A A kind of water-resistant type animal bone glue adhesive 常州五荣化工有限公司 2018-12-28 CN claimed
CN-107614585-A Plasticizer composition, resin composition and method for producing the same 株式会社LG化学 2018-01-19 CN claimed
CN-107531938-A Plasticizer composition, resin composition and method for producing the same 株式会社LG化学 2018-01-02 CN claimed
CN-107531937-A Plasticizer composition, resin composition and method for producing the same 株式会社LG化学 2018-01-02 CN claimed
CN-107151419-A A kind of high tenacity cold mixing bituminous epoxy binding agent and preparation method thereof 河海大学 2017-09-12 CN claimed
US-20170008978-A1 Family of Pain Producing Substances and Methods to Produce Novel Analgesic Drugs UNIV TEXAS (US) 2017-01-12 US claimed
US-20140308292-A1 FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-10-16 US claimed
US-20110311545-A1 FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2011-12-22 US claimed
EP-2381940-A2 A NEW FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS Board of Regents, The University of Texas System (US) 2011-11-02 EP claimed
WO-2010062900-A2 A NEW FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-03 WO claimed
CN-118344256-A Synthesis and application of anti-migration bio-based environment-friendly plasticizer 江南大学 2024-07-16 CN disclosed
CN-116969965-B Epoxy linoleic acid isosorbide heat stabilizer and preparation and application thereof 北京工商大学 2024-03-12 CN disclosed
US-20110311545-A1 FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2011-12-22 US disclosed
EP-2381940-A2 A NEW FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS Board of Regents, The University of Texas System (US) 2011-11-02 EP disclosed
WO-2010062900-A2 A NEW FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110311545-A1 FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS ALOX15B, ALOX5, ALOX15 MAPT 3675/4885ALDH1A1 270/4885PPARG 532/4885
US-20170008978-A1 Family of Pain Producing Substances and Methods to Produce Novel Analgesic Drugs ALOX15B, ALOX5, ALOX15 MAPT 3675/4885ALDH1A1 270/4885PPARG 532/4885
US-20140308292-A1 FAMILY OF PAIN PRODUCING SUBSTANCES AND METHODS TO PRODUCE NOVEL ANALGESIC DRUGS ALOX15B, ALOX5, ALOX15 MAPT 3675/4885ALDH1A1 270/4885PPARG 532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.