Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24447316 | 0.93 | TAS1R3 (0.38) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL15912333 | 0.82 | ALDH1A1 (0.39) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL13311451 | 0.82 | NPC1 (0.42) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL24932464 | 0.77 | ALDH1A1 (0.35) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL8980389 | 0.77 | NPC1 (0.41) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL24253408 | 0.76 | LMNA (0.38) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 | |
| SCHEMBL24984324 | 0.76 | TGFBR1 (0.35) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL21025996 | 0.76 | NPC1 (0.39) | TAS1R3TAS1R1NPC1RAB9AMEN1 | |
| SCHEMBL6298458 | 0.76 | ALDH1A1 (0.34) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 | |
| SCHEMBL24611377 | 0.75 | ALDH1A1 (0.33) | TAS1R3TAS1R1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174542-A1 | HETEROCYCLIC ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174542-A1 | HETEROCYCLIC ANTIVIRAL AGENTS | ACE, SARS1, ACE2 | TAS1R3 3749/4885TAS1R1 2985/4885NPC1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.