Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27022587 | 0.86 | L3MBTL3 (0.51) | HSD11B1KMT2AMEN1L3MBTL3MBTD1 | |
| SCHEMBL3455469 | 0.85 | ACHE (0.68) | HSD11B1KMT2AMEN1L3MBTL3L3MBTL1 | |
| SCHEMBL22503846 | 0.84 | MAPT (0.56) | L3MBTL3ACHEPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL14600511 | 0.80 | HTT (0.66) | HSD11B1KMT2AMEN1ACHEPOLB | |
| SCHEMBL31003116 | 0.77 | HSD11B1 (0.57) | HSD11B1KMT2AMEN1L3MBTL3MBTD1 | |
| SCHEMBL25498559 | 0.77 | L3MBTL3 (0.87) | HSD11B1KMT2AMEN1L3MBTL3MBTD1 | |
| SCHEMBL21977131 | 0.77 | MEN1 (0.59) | HSD11B1KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL11376680 | 0.77 | HPGD (0.76) | HSD11B1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL13727317 | 0.77 | ALDH1A1 (0.55) | HSD11B1KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL16219378 | 0.77 | ALDH1A1 (0.54) | HSD11B1KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |