Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256606 | 0.82 | SCN5A (0.31) | SCN5ASCN9A | |
| SCHEMBL27598069 | 0.80 | KEAP1 (0.53) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL290570 | 0.80 | KEAP1 (0.53) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL31349524 | 0.80 | KEAP1 (0.53) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL8357219 | 0.76 | SCN5A (0.36) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL4966985 | 0.76 | ALDH1A1 (0.36) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL9928617 | 0.74 | AGBL2 (0.39) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL168694 | 0.74 | CASP1 (0.42) | SCN5ASCN9A | |
| SCHEMBL9927092 | 0.74 | SCN5A (0.36) | SCN5ASCN9AAGBL2KEAP1NFE2L2 | |
| SCHEMBL27604299 | 0.73 | KEAP1 (0.46) | SCN5ASCN9AAGBL2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012028645-A1 | METHOD FOR THE PRODUCTION OF 5-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBONITRILE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-08 | — | — | WO | disclosed |