Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ASPH | Q12797 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598069 | 1.00 | KEAP1 (0.53) | KEAP1NFE2L2SMN1; SMN2LMNAASPH | |
| SCHEMBL31349524 | 1.00 | KEAP1 (0.53) | KEAP1NFE2L2SMN1; SMN2LMNAASPH | |
| SCHEMBL27604299 | 0.91 | KEAP1 (0.46) | KEAP1NFE2L2SMN1; SMN2LMNAASPH | |
| SCHEMBL29172965 | 0.84 | KEAP1 (0.41) | KEAP1NFE2L2SMN1; SMN2LMNAKDM4E | |
| SCHEMBL8357219 | 0.84 | SCN5A (0.36) | KEAP1NFE2L2SMN1; SMN2LMNAASPH | |
| SCHEMBL4966985 | 0.84 | ALDH1A1 (0.36) | KEAP1NFE2L2SMN1; SMN2LMNAASPH | |
| SCHEMBL168694 | 0.82 | CASP1 (0.42) | SCN5ASCN9ACASP1 | |
| SCHEMBL9928617 | 0.82 | AGBL2 (0.39) | KEAP1NFE2L2SMN1; SMN2KDM4EHCAR2 | |
| SCHEMBL256609 | 0.80 | SCN5A (0.34) | KEAP1NFE2L2HCAR2AGBL2SCN5A | |
| SCHEMBL915781 | 0.79 | SMN1; SMN2 (0.48) | KEAP1NFE2L2SMN1; SMN2LMNAASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 581 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878537-B | Synthesis method of intermediate for substituted tricyclic PRMT5 inhibitor | 淄博百极荣创医药科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118878537-A | Synthesis method of intermediate for substituted tricyclic PRMT5 inhibitor | 淄博百极荣创医药科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-117567461-A | Preparation method of vitamin Li Xigu intermediate | 佛山奕安赛医药科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-115073363-B | 5-fluoro-2-methoxy nicotinaldehyde and preparation method thereof | 宁波申泰生物科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-115073363-A | 5-fluoro-2-methoxy nicotinaldehyde and preparation method thereof | 宁波申泰生物科技有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114907315-A | Synthesis method of Selitrectinib intermediate | 重庆医科大学 | 2022-08-16 | — | — | CN | claimed |
| CN-215540758-U | Quick synthesizer is used in production of 2-chlorine-5-fluorine nicotinic acid | 苏州兴华高新材料科技有限公司 | 2022-01-18 | — | — | CN | claimed |
| CN-215215035-U | Blowdown valve is used in 2-chlorine-5-fluorine nicotinic acid production | 苏州兴华高新材料科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-215196539-U | Mixing kettle used in production process of 2-chloro-5-fluoronicotinic acid | 苏州兴华高新材料科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-109212051-B | Gas chromatography-mass spectrometry combined method for determining nine trace amounts of halogenated nicotinic acid in drinking water | 丁立平 | 2021-11-19 | — | — | CN | claimed |
| CN-113354638-A | Preparation method of 5-fluoro-3-iodo-1H-pyrazolo [3,4-b ] pyridine | 天津敬康生物科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-109212051-A | The gas chromatography-mass spectrometry of nine kinds of halogenated niacin of trace in a kind of measurement drinking water | 丁立平 | 2019-01-15 | — | — | CN | claimed |
| CN-103012257-A | Quinolone intermediate synthesis technology | Sheng yinuo | 2013-04-03 | — | — | CN | claimed |
| CN-101343366-A | Nano-laminal compound with regular array of pyridine and its derivant, and preparation thereof | UNIV SHANGHAI (CN) | 2009-01-14 | — | — | CN | claimed |
| CN-100355732-C | Preparation of 2-Cl-5-F-nicotinate and nicotonic acid | YAOMING KANGDE MEDICINE DEVELO (CN) | 2007-12-19 | — | — | CN | claimed |
| CN-100355733-C | Industrialized method for preparing 2-chlorine-5-fluorin-nicotinic aicd | YAOMINGKANGDE NEW MEDICINE DEV (CN) | 2007-12-19 | — | — | CN | claimed |
| CN-1626519-A | Industrialized method for preparing 2-chlorine-5-fluorin-nicotinic aicd | YAOMINGKANGDE NEW MEDICINE DEV (CN) | 2005-06-15 | — | — | CN | claimed |
| CN-1613849-A | Preparation of 2-Cl-5-F-nicotinate and nicotonic acid | YAOMING KANGDE MEDICINE DEVELO (CN) | 2005-05-11 | — | — | CN | claimed |
| CN-1003236-B | Preparation method of 6, 7-disubstituted-1-cyclopropyl-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid | 拜尔公司 | 1989-02-08 | — | — | CN | claimed |
| CN-86100126-A | 6, the two replacement-1-cyclopropyl of 7--1,4 dihydro-4-oxo-1, the preparation method and the application thereof of 8-naphthyridines-3-carboxylic acid | — | 1986-07-09 | — | — | CN | claimed |