Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.53 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14876141 | 0.84 | POLB (0.49) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL522124 | 0.83 | LMNA (0.48) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL22451330 | 0.83 | TDP1 (0.57) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL523171 | 0.83 | ALDH1A1 (0.56) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL521944 | 0.83 | LMNA (0.48) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL14876303 | 0.83 | CASP1 (0.55) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL523176 | 0.83 | CASP3 (0.55) | LPAR1LPAR3PIN1PIN4ALDH1A1 | |
| SCHEMBL124512 | 0.82 | LPAR1 (0.73) | LPAR1LPAR3ALDH1A1POLBCHRM2 | |
| SCHEMBL524126 | 0.82 | ALDH1A1 (0.67) | ALDH1A1POLBKDM4EMAPTMEN1 | |
| SCHEMBL10584655 | 0.81 | LPAR1 (0.55) | LPAR1LPAR3CHRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183180-A1 | PROCESS OF MAKING ROXADUSTAT | SUZHOU PENGXU PHARMATECH CO., LTD. (CN) | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183180-A1 | PROCESS OF MAKING ROXADUSTAT | CYP2B6, UGT1A6, CYP2D6 | LPAR1 2106/4885LPAR3 2201/4885PIN1 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.