SCHEMBL25673199

SCHEMBL25673199

CC1(c2ccc(I)cc2)N=N1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.33
OPRM1 P35372 1/20 0.32
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25245033 0.68 OPRM1 (0.40) HDAC8OPRM1HTR6
SCHEMBL19730855 0.68 HTR6 (0.34) HDAC8OPRM1HTR6
SCHEMBL17625253 0.67 HSD17B1 (0.32)
SCHEMBL11489793 0.65 OPRM1 (0.34) OPRM1
SCHEMBL67142 0.65
SCHEMBL10597056 0.65 HDAC8 (0.50) HDAC8
SCHEMBL665550 0.64 KCNH2 (0.46) OPRM1
SCHEMBL1932565 0.64 TSHR (0.38) OPRM1
SCHEMBL4659933 0.64 KIF11 (0.45)
SCHEMBL21042475 0.61 TPMT (0.31) HDAC8OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023095841-A1 METHOD FOR EVALUATING DNA-ENCODED LIBRARY 日産化学株式会社 2023-06-01 WO disclosed