Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054793 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL4014963 | 0.95 | ALDH1A1 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL2330898 | 0.95 | ALDH1A1 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| SCHEMBL9998422 | 0.81 | EPHX1 (0.36) | SLC6A2SLC6A3SLC6A4ALDH1A1FDPS | |
| SCHEMBL27695492 | 0.80 | NAAA (0.43) | — | |
| SCHEMBL9685631 | 0.79 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL16191692 | 0.79 | EPHX1 (0.35) | SLC6A2SLC6A3SLC6A4ALDH1A1FDPS | |
| SCHEMBL4124514 | 0.78 | KMT2A (0.44) | SLC6A2SLC6A3SLC6A4ALDH1A1KMT2A | |
| SCHEMBL9568980 | 0.78 | ALDH1A1 (0.38) | SLC6A2SLC6A3SLC6A4ALDH1A1SOAT1 | |
| Hydrochloric Acid SCHEMBL8933166 | 0.78 | SLC6A3 (0.43) | SLC6A2SLC6A3SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352150-A1 | Process for the preparation of meta-substituted fluoro or alkyl benzene derivatives | RHONE-POULENC CHIMIE (FR) | 1990-01-24 | — | — | EP | claimed |
| EP-3019012-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2016-05-18 | — | — | EP | disclosed |
| WO-2015004040-A1 | USE OF SELECTED PYRIDONE CARBOXAMIDES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-01-15 | — | — | WO | disclosed |
| EP-2066659-B1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2383267-A1 | Substituted sulfonamide derivatives | Grünenthal GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | disclosed |
| EP-1706413-A1 | TRICYCLIC BENZAZEPINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS USED FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | Bayer HealthCare AG (DE) | 2006-10-04 | — | — | EP | disclosed |
| EP-1583757-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2005068472-A1 | TRICYCLIC BENZAZEPINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS USED FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2005-07-28 | — | — | WO | disclosed |
| EP-0311135-B1 | HETEROCYCLIC SUBSTITUTED AZOLES AND AZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AN AGENT WITH HERBICIDE ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0349748-B1 | SUBSTITUTED N-ARYL-NITROGEN CONTAINING HETEROCYCLES | BAYER AG (DE) | 1992-11-19 | — | — | EP | disclosed |
| EP-0427031-A2 | N-aryl-nitrogen heterocycles | BAYER AG (DE) | 1991-05-15 | — | — | EP | disclosed |
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |
| EP-0384192-A2 | N-Aryl nitrogen heterocycles having fluorine-containing substituents | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0364797-A2 | N-aryl-nitrogenated heterocycles, process for their preparation and their use as herbicides | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0363585-A1 | N-aryl nitrogen heterocycles | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |
| EP-0349748-A1 | Substituted N-aryl-nitrogen containing heterocycles | BAYER AG (DE) | 1990-01-10 | — | — | EP | disclosed |
| EP-0311135-A2 | Heterocyclic substituted azoles and azines, process for their preparation and their use as an agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-04-12 | — | — | EP | disclosed |
| EP-0268797-A2 | Halogencyclopropyl compounds, their preparation and herbicidal application | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-06-01 | — | — | EP | disclosed |