SCHEMBL2567644

SCHEMBL2567644

O=C(Nc1ccc(F)cc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 1.00
NPC1 O15118 6/20 1.00
MEN1 O00255 6/20 0.86
KMT2A Q03164 6/20 0.86
POLB P06746 3/20 0.86
TDP1 Q9NUW8 1/20 0.86
MITF O75030 1/20 0.76
KCNK3 O14649 1/20 0.74
KCNK9 Q9NPC2 1/20 0.74
PTPN1 P18031 3/20 0.72
MAPT P10636 2/20 0.69
ALDH1A1 P00352 1/20 0.69
CYP2C9 P11712 1/20 0.69
SIRT1 Q96EB6 1/20 0.69
KDM4E B2RXH2 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.67
HPGD P15428 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL30758609 0.98 RAB9A (0.96) RAB9ANPC1MEN1KMT2APOLB
Hydrochloric Acid SCHEMBL5797259 0.98 RAB9A (0.96) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL4783063 0.92 MEN1 (0.86) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL10684470 0.90 PTPN1 (0.88) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL126415 0.89 PTPN1 (0.87) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL14715824 0.87 NPC1 (0.88) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL18103163 0.87 NPC1 (0.88) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL4635501 0.86 MITF (1.00) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL3639776 0.86 MITF (1.00) RAB9ANPC1MEN1KMT2APOLB
SCHEMBL26953087 0.85 PTPN1 (0.88) RAB9ANPC1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746415-B Polymorphs of triazole antifungal compound PC945 普尔莫赛德有限公司 2025-04-11 CN claimed
CN-112375073-B Antifungal compounds 普尔莫赛德有限公司 2024-04-16 CN claimed
CN-108135871-B Amine naphthoquinone compounds and pharmaceutical compositions for blocking ubiquitination-proteasome system in diseases 博蔚医药生物科技股份有限公司 2022-11-04 CN claimed
CN-110167556-A Thio-hydantoin androgen receptor antagonist for treating cancer 詹森药业有限公司 2019-08-23 CN claimed
EP-3227277-A1 ANTIMYCOTIC COMPOUND Pulmocide Limited (GB) 2017-10-11 EP claimed
WO-2016087878-A1 ANTIMYCOTIC COMPOUND PULMOCIDE LIMITED (GB) 2016-06-09 WO claimed
EP-2097379-A1 CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS Wyeth a Corporation of the State of Delaware (US) 2009-09-09 EP claimed
WO-2008073936-A1 CARBOXAMIDE DERIVATIVES AS ION CHANNEL MODULATORS WYETH (US) 2008-06-19 WO claimed
EP-1042276-A1 THIOUREA COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY LLC (US) 2000-10-11 EP claimed
WO-1999032433-A1 THIOUREA AND BENZAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1999-07-01 WO claimed
US-20260125340-A1 METHOD FOR PREPARING AMIDES FROM ESTERS BASF SE (DE) 2026-05-07 US disclosed
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP disclosed
US-5428163-A Luminides; chemiluminescence; redox system, releasing free drug MILLS RANDELL L (US) 1995-06-27 US disclosed
EP-0646566-A1 Process for the preparation of acid chloride compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-04-05 EP disclosed
EP-0414730-A4 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS 1993-06-16 EP disclosed
EP-0414730-A1 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS Mills, Randell L. (US) 1991-03-06 EP disclosed
WO-1989009833-A1 LUMINIDE AND MACROLUMINIDE CLASS OF PHARMACEUTICALS MILLS RANDELL L (US) 1989-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125340-A1 METHOD FOR PREPARING AMIDES FROM ESTERS CBR1, CBR3, SCO2 RAB9A 1069/4885NPC1 549/4885MEN1 2007/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD RAB9A 567/4885NPC1 3361/4885MEN1 1180/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD RAB9A 567/4885NPC1 3361/4885MEN1 1180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.