SCHEMBL25699115

SCHEMBL25699115

c1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-n3c4ccccc4c4ccc([Si](c5ccccc5)(c5ccccc5)c5ccccc5)cc43)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
FOLH1 Q04609 1/20 0.33
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAT2A P31153 2/20 0.31
HSD17B10 Q99714 1/20 0.31
KMT2A Q03164 2/20 0.31
MAPK8 P45983 2/20 0.31
IL1R1 P14778 1/20 0.31
TSHR P16473 1/20 0.31
KDR P35968 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPK9 P45984 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17463311 0.98 L3MBTL1 (0.55) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL19870168 0.96 L3MBTL1 (0.51) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL19870172 0.94 L3MBTL1 (0.50) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL24064785 0.94 KDM4E (0.46) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL24064821 0.94 KDM4E (0.52) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL24987484 0.94 KDM4E (0.52) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL25806675 0.94 L3MBTL1 (0.60) KDM4EATML3MBTL1PTPN1ALDH1A1
SCHEMBL5466449 0.94 L3MBTL1 (0.59) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL5465450 0.94 L3MBTL1 (0.59) KDM4EATML3MBTL1FOLH1PTPN1
SCHEMBL30414926 0.94 L3MBTL1 (0.59) KDM4EATML3MBTL1FOLH1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-20230174559-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230174559-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174559-A1 LIGHT-EMITTING DEVICE INCLUDING HETEROCYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE, AND THE HETEROCYCLIC COMPOUND CRY1, CRY2, LAGE3 KDM4E 2703/4885ATM 3571/4885L3MBTL1 1696/4885
US-20230192729-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE LAGE3, EMC1, CYP2E1 KDM4E 2517/4885ATM 3931/4885L3MBTL1 1280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.