SCHEMBL2569919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2568750	0.90	L3MBTL1 (0.45)	NAMPTBACE1HDAC3HDAC1HDAC2
	SCHEMBL3143368	0.89	BACE1 (0.40)	NAMPTBACE1KMT2ARXFP1
	SCHEMBL2570316	0.89	BACE1 (0.44)	NAMPTBACE1HDAC3HDAC1HDAC2
	SCHEMBL3143382	0.89	BACE1 (0.40)	NAMPTBACE1KMT2ARXFP1
	SCHEMBL2566851	0.88	BACE1 (0.39)	NAMPTBACE1HDAC1RXFP1HDAC6
	SCHEMBL2563762	0.88	NAMPT (0.45)	NAMPTBACE1HDAC3HDAC1HDAC2
	SCHEMBL2566854	0.88	BACE1 (0.39)	NAMPTBACE1HDAC1RXFP1HDAC6
	SCHEMBL2571354	0.88	ROCK2 (0.44)	NAMPTBACE1L3MBTL1KMT2APDK2
	SCHEMBL5316055	0.86	LMNA (0.43)	NAMPTBACE1L3MBTL1KMT2ADRD2
	SCHEMBL2568771	0.86	NAMPT (0.45)	NAMPTBACE1L3MBTL1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.