SCHEMBL25709690

SCHEMBL25709690

Brc1ccc(C23C[C@H]4C[C@@H](C2)C[C@@H](C3)C4)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
P2RX7 Q99572 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HTT P42858 1/20 0.33
HTR6 P50406 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD11B1 P28845 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
HPGD P15428 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26006724 1.00 ALDH1A1 (0.35) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL23625607 0.90 GRIN2D (0.39) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL13004841 0.79 ALDH1A1 (0.35) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL13004762 0.79 MEN1 (0.47) ALDH1A1MEN1KMT2AHTTKDM4E
SCHEMBL25720543 0.78 RXFP1 (0.32) HTR6RXFP1
SCHEMBL30724856 0.77 HTR2A (0.42) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL1939201 0.77 HTR2A (0.42) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL25720541 0.77 RXFP1 (0.31) HTR6RXFP1
SCHEMBL26272377 0.76 LMNA (0.45) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL24617657 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-05 US disclosed
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11746093-B2 Nitrogen-containing compound, electronic element, and electronic device SLC43A1, SLC7A5, L1CAM ALDH1A1 3782/4885LMNA 1530/4885GRIN2D 468/4885
US-20230192627-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE SLC43A1, SLC7A5, L1CAM ALDH1A1 3782/4885LMNA 1530/4885GRIN2D 468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.