SCHEMBL1939201

SCHEMBL1939201

Brc1ccccc1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
P2RX7 Q99572 1/20 0.41
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
HSD11B1 P28845 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30724856 1.00 HTR2A (0.42) HTR2AHTR2CP2RX7ALDH1A1LMNA
SCHEMBL28877624 0.84 ALDH1A1 (0.37) HTR2AHTR2CP2RX7ALDH1A1LMNA
SCHEMBL25709690 0.77 ALDH1A1 (0.35) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL26006724 0.77 ALDH1A1 (0.35) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL25125099 0.75 ALDH1A1 (0.48) ALDH1A1LMNAGRIN2DGRIN3BGRIN1
SCHEMBL345587 0.75 MEN1 (0.48) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL9721521 0.75 HSD11B1 (0.42) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL5610573 0.75 ALDH1A1 (0.39) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL29809124 0.75 MEN1 (0.48) P2RX7ALDH1A1LMNAGRIN2DGRIN3B
SCHEMBL32685217 0.75 GRIN2D (0.42) ALDH1A1LMNAGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776854-A Organic compound and application thereof in electronic device 浙江光昊光电科技有限公司 2024-03-29 CN disclosed
CN-117263813-A Light-emitting element and amine compound for light-emitting element 三星显示有限公司 2023-12-22 CN disclosed
US-20230413663-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-21 US disclosed
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-09 US disclosed
US-11744147-B2 Light emitting diode and display device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
US-11744147-B2 Light emitting diode and display device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-29 US disclosed
EP-2331495-B1 PROCESS FOR MANUFACTURING ADAMANTANE DERIVATIVES WITH HIGH YIELD MERZ PHARMA GMBH & CO KGAA (DE) 2016-01-27 EP disclosed
US-8796491-B2 Process for manufacturing adamantane derivatives with high yield MERZ PHARMA GMBH & CO. KGAA (DE) 2014-08-05 US disclosed
CN-102892755-A Therapeutic compounds UNIV WAYNE STATE 2013-01-23 CN disclosed
EP-1578839-A1 ORGANIC COMPOSITIONS Honeywell International, Inc. (US) 2005-09-28 EP disclosed
CN-1643030-A Low dielectric constant materials and methods of preparation thereof HONEYWELL INT INC (US) 2005-07-20 CN disclosed
WO-2005010071-A1 ORGANIC COMPOSITIONS HONEYWELL INTERNATIONAL INC (US) 2005-02-03 WO disclosed
EP-1466356-A2 ORGANIC COMPOSITIONS Honeywell International Inc. (US) 2004-10-13 EP disclosed
EP-1466355-A2 ORGANIC COMPOSITIONS Honeywell International Inc. (US) 2004-10-13 EP disclosed
CN-1494559-A organic composition 霍尼韦尔国际公司 2004-05-05 CN disclosed
US-6713590-B2 FABRICATED FROM FIRST COMPONENT COMPRISING POLYMERIC STRAND AND SECOND COMPONENT COMPRISING MOLECULE HAVING CENTRAL PORTION WITH AT LEAST THREE ARMS EXTENDING THEREFROM HONEYWELL INTERNATIONAL INC. 2004-03-30 US disclosed
WO-2003061029-A2 ORGANIC COMPOSITIONS HONEYWELL INTERNATIONAL INC. (US) 2003-07-24 WO disclosed
WO-2003060979-A2 ORGANIC COMPOSITIONS FOR LOW DIELECTRIC CONSTANT MATERIALS HONEYWELL INTERNATIONAL INC. (US) 2003-07-24 WO disclosed
US-20020037941-A1 Low dielectric constant materials with polymeric networks LAU KREISLER S (US) 2002-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11744147-B2 Light emitting diode and display device including the same ALDH1A2, STRA6, DCX HTR2A 1468/4885HTR2C 2261/4885P2RX7 1928/4885
US-20230363261-A1 LIGHT EMITTING DIODE AND DISPLAY DEVICE INCLUDING THE SAME ALDH1A2, STRA6, DCX HTR2A 1468/4885HTR2C 2261/4885P2RX7 1928/4885
US-20230413663-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME EFNA1, SLC1A2, ALDH1A2 HTR2A 198/4885HTR2C 143/4885P2RX7 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.