Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Uc 781 SCHEMBL2670342 | 0.80 | LMNA (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| Uc 781 SCHEMBL29838161 | 0.80 | LMNA (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL30101193 | 0.75 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL599254 | 0.75 | ADRA2A (0.35) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6822542 | 0.71 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30367409 | 0.71 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL13138528 | 0.69 | ADRA2A (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL6409879 | 0.67 | ADRA2A (0.49) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL13138533 | 0.67 | BRD4 (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17798951 | 0.67 | LMNA (0.42) | LMNASMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230201246-A1 | METAL COMPOSITIONS AND METHODS OF USE THEREOF | UNIVERSITY OF MASSACHUSETTS | 2023-06-29 | — | — | US | disclosed |
| US-20230201246-A1 | METAL COMPOSITIONS AND METHODS OF USE THEREOF | UNIVERSITY OF MASSACHUSETTS | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230201246-A1 | METAL COMPOSITIONS AND METHODS OF USE THEREOF | SOD1, SOD3, SLC30A5 | ADRA2A 4758/4885ADRA2B 4843/4885ADRA2C 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.