Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | FSHR | P23945 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12283365 | 0.78 | MAPT (0.54) | MEN1MAPTTHRBKMT2AKDM4A | |
| SCHEMBL257152 | 0.73 | HSPA9 (0.41) | MEN1MAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30242141 | 0.72 | P2RX7 (0.39) | MEN1MAPTTHRBKMT2AKDM4A | |
| SCHEMBL28980136 | 0.72 | P2RX7 (0.39) | MEN1MAPTTHRBKMT2AKDM4A | |
| SCHEMBL22298319 | 0.69 | FSHR (0.32) | MAPTALDH1A1LMNAFSHRCHEK1 | |
| SCHEMBL18439059 | 0.69 | HSD11B1 (0.36) | MEN1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL18054870 | 0.69 | HSD11B1 (0.36) | MEN1MAPTKMT2APOLBSMN1; SMN2 | |
| SCHEMBL6287579 | 0.69 | MEN1 (0.39) | MEN1MAPTTHRBKMT2AKDM4A | |
| SCHEMBL9067029 | 0.68 | MAPT (0.44) | MEN1MAPTTHRBKMT2AKDM4A | |
| SCHEMBL257150 | 0.66 | ROCK1 (0.43) | MEN1MAPTTHRBKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029763-A1 | DIAMINE, POLYIMIDE PRECURSOR, POLYIMIDE, LIQUID-CRYSTAL ALIGNMENT MATERIAL, LIQUID-CRYSTAL ALIGNMENT FILM, AND LIQUID-CRYSTAL DISPLAY ELEMENT | 日産化学工業株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |