SCHEMBL6287579

SCHEMBL6287579

CC1N(CC(=O)O)c2ccc(N)cc2C1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
THRB P10828 3/20 0.39
POLB P06746 2/20 0.39
RECQL P46063 2/20 0.39
KDM4A O75164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
FSHR P23945 1/20 0.38
GFER P55789 2/20 0.33
NOX1 Q9Y5S8 1/20 0.33
GNRHR P30968 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
CHEK1 O14757 2/20 0.32
PRKD3 O94806 2/20 0.32
MAP4K4 O95819 2/20 0.32
RET P07949 2/20 0.32
MET P08581 2/20 0.32
PDGFRA P16234 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12283365 0.72 MAPT (0.54) MEN1KMT2AMAPTTHRBPOLB
SCHEMBL257148 0.69 MEN1 (0.35) MEN1KMT2AMAPTTHRBPOLB
SCHEMBL11516280 0.69 KMO (0.42) MEN1KMT2AMAPTTHRBPOLB
SCHEMBL28448899 0.68 SLC6A9 (0.33) MEN1KMT2APOLBDRD2DRD4
SCHEMBL11671389 0.68 ALDH1A1 (0.45) MEN1KMT2AMAPTPOLBSMN1; SMN2
SCHEMBL28898622 0.68 SLC6A9 (0.33) MEN1KMT2APOLBDRD2DRD4
SCHEMBL29849416 0.68 FDPS (0.41) KMT2AMAPTPOLBGAATDP1
SCHEMBL5133368 0.66 DRD2 (0.43) MEN1KMT2AMAPTTHRBPOLB
SCHEMBL29521317 0.66 DRD2 (0.43) MEN1KMT2AMAPTTHRBPOLB
SCHEMBL3877741 0.65 GNRHR (0.40) MEN1KMT2AMAPTTHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same LANG GERARD (FR) 2004-05-13 US claimed
US-20030167579-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-09-11 US claimed
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030028977-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-02-13 US claimed
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-01-16 US claimed
EP-1263398-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-12-11 EP claimed
EP-1263399-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-12-11 EP claimed
EP-1181004-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-02-27 EP claimed
EP-1181005-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2002-02-27 EP claimed
WO-2001066071-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066070-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066069-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
WO-2001066072-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO claimed
US-6890362-B2 Oxidation dyeing composition for keratinous fibers and dyeing method using same L'OREAL, S.A. (FR) 2005-05-10 US disclosed
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same LANG GERARD (FR) 2004-05-13 US disclosed
US-20030167579-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same L'OREAL S.A. (FR) 2003-09-11 US disclosed
WO-2001066069-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO disclosed
WO-2001066068-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES WITH A PARTICULAR PARAPHENYLENEDIAMINE DERIVATIVE AND A PARTICULAR DIRECT DYEING AGENT L'OREAL (FR) 2001-09-13 WO disclosed
WO-2001066072-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO disclosed
WO-2001066070-A1 OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent KRT18, CDC73, DAO MEN1 3252/4885KMT2A 1698/4885MAPT 1020/4885
US-20030028977-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, NDUFB5, NDUFB4 MEN1 3505/4885KMT2A 1509/4885MAPT 805/4885
US-20030167579-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, PPOX, COXFA4L2 MEN1 3500/4885KMT2A 2526/4885MAPT 878/4885
US-20040088798-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, OAT, ACOX1 MEN1 4145/4885KMT2A 1920/4885MAPT 1555/4885
US-20030009835-A1 Oxidation dyeing composition for keratinous fibres and dyeing method using same KRT18, PPOX, NDUFB5 MEN1 3718/4885KMT2A 2658/4885MAPT 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.