Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099146 | 0.75 | CYP2C19 (0.51) | HSD17B10SMN1; SMN2RXFP1CYP1A2CYP2C9 | |
| SCHEMBL22374561 | 0.73 | HRH4 (0.43) | HSD17B10SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL24453540 | 0.70 | GHSR (0.37) | HSD17B10SMN1; SMN2SIRT1PARP1HTR2A | |
| SCHEMBL27624769 | 0.70 | NQO2 (0.43) | HSD17B10SMN1; SMN2RXFP1CYP1A2NPSR1 | |
| SCHEMBL24201870 | 0.68 | HSD17B10 (0.75) | HSD17B10SMN1; SMN2RXFP1CYP1A2CYP2C9 | |
| SCHEMBL20125059 | 0.68 | DAO (0.60) | MAPTKDM4EALDH1A1HTTPARP1 | |
| SCHEMBL16065330 | 0.68 | DAO (0.37) | RXFP1CYP1A2CYP2C9CYP2C19PRNP | |
| SCHEMBL20382321 | 0.68 | ALDH1A1 (0.64) | HSD17B10SMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL21870108 | 0.67 | ALDH1A1 (0.38) | HSD17B10SMN1; SMN2RXFP1CYP1A2CYP2C9 | |
| SCHEMBL19412656 | 0.67 | NOS2 (0.48) | SMN1; SMN2CYP1A2KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |