Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | GUSB | P08236 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614837 | 0.82 | ALDH1A1 (0.41) | TNFMPOHTR1AALDH1A1CES2 | |
| SCHEMBL4393222 | 0.79 | HTR1A (0.40) | TNFMPOHTR1AALDH1A1CES2 | |
| SCHEMBL1732171 | 0.77 | HTR2A (0.47) | ALDH1A1CES2CES1ALOX15 | |
| SCHEMBL25423230 | 0.77 | CES2 (0.39) | TNFALDH1A1CES2CES1GUSB | |
| SCHEMBL25241237 | 0.77 | GPR84 (0.47) | HTR1ACES2CES1 | |
| SCHEMBL12215170 | 0.77 | KAT6A (0.30) | — | |
| SCHEMBL16597349 | 0.75 | NR4A2 (0.49) | ALDH1A1LMNA | |
| SCHEMBL12215154 | 0.72 | TNF (0.35) | TNFMPOCES2CES1ADRA2A | |
| SCHEMBL12513768 | 0.72 | TNF (0.35) | TNFCES2CES1ADRA2ACLCN2 | |
| SCHEMBL13325438 | 0.71 | BRPF1 (0.33) | TNFMPOALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115166-A1 | COMPOUNDS | Psylo Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |