SCHEMBL25752378

SCHEMBL25752378

Cc1ccc(-n2c3cc(C(C)C)ccc3c(=O)c3cc4c(cc32)c(=O)c2ccc(C(C)C)cc2n4-c2ccc(C)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
USP14 P54578 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAT2A P31153 1/20 0.37
HTT P42858 1/20 0.36
MAPT P10636 1/20 0.36
MGLL Q99685 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
DRD1 P21728 1/20 0.35
DRD5 P21918 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RAB9A P51151 1/20 0.34
TBK1 Q9UHD2 2/20 0.34
GSK3A P49840 2/20 0.34
GSK3B P49841 2/20 0.34
P2RX4 Q99571 1/20 0.34
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752390 0.92 MGLL (0.42) TDP1USP14KDM4EALDH1A1MAT2A
SCHEMBL25752385 0.91 TDP1 (0.42) TDP1USP14KDM4EALDH1A1MAT2A
SCHEMBL25752415 0.88 MAT2A (0.35) TDP1USP14KDM4EALDH1A1MAT2A
SCHEMBL25752365 0.87 MAT2A (0.50) KDM4EALDH1A1MAT2AL3MBTL1GSK3A
SCHEMBL25752433 0.85 MAT2A (0.36) TDP1USP14KDM4EALDH1A1MAT2A
SCHEMBL25752400 0.85 PPARG (0.44) TDP1USP14KDM4EALDH1A1MAT2A
SCHEMBL25752370 0.84 HTT (0.41) TDP1KDM4EALDH1A1HTTMAPT
SCHEMBL25752419 0.82 NR1I2 (0.34) TDP1KDM4EALDH1A1HTTMAPT
SCHEMBL25752377 0.82 MGLL (0.37) KDM4EALDH1A1HTTMAPTMGLL
SCHEMBL25752386 0.82 ALDH1A1 (0.46) TDP1USP14KDM4EALDH1A1MAT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed