SCHEMBL25752667

SCHEMBL25752667

CC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)CC1ON=C(C)C

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TK1 P04183 5/20 0.53
RNASE1 P07998 1/20 0.53
LMNA P02545 2/20 0.53
TSHR P16473 2/20 0.53
ALB P02768 1/20 0.53
PKM P14618 1/20 0.53
BLM P54132 1/20 0.53
PMP22 Q01453 1/20 0.53
CYP2D6 P10635 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10446528 0.92 RNASE1 (0.63) TK1RNASE1LMNATSHRALB
SCHEMBL10292555 0.92 RNASE1 (0.63) TK1RNASE1LMNATSHRALB
SCHEMBL25492060 0.88 LMNA (0.55) TK1RNASE1LMNATSHRPMP22
SCHEMBL12932156 0.85 RNASE1 (0.63) TK1RNASE1
SCHEMBL15498284 0.85 RNASE1 (0.63) TK1RNASE1
SCHEMBL15498298 0.85 RNASE1 (0.63) TK1RNASE1
SCHEMBL15187886 0.85 RNASE1 (0.63) TK1RNASE1
SCHEMBL25752765 0.85 TOP2A (0.60) TK1RNASE1
SCHEMBL12087585 0.84 TK1 (0.60) TK1RNASE1LMNAALBPKM
SCHEMBL12015131 0.84 TK1 (0.60) TK1RNASE1LMNAALBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES Nuclera Nucleics Ltd. (GB) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES RNGTT, POLM, POLRMT TK1 259/4885RNASE1 26/4885LMNA 568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.