SCHEMBL25754502

SCHEMBL25754502

CC#CC(O)CCC(N)CCN1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HRH3 Q9Y5N1 2/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
ANPEP P15144 1/20 0.30
ERAP2 Q6P179 1/20 0.30
TSHR P16473 1/20 0.30
CYP1A2 P05177 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754525 0.88 HRH3 (0.32) LMNAHRH3ALDH1A1CYP1A2
SCHEMBL25754484 0.86 MEN1 (0.41) MEN1KMT2AALDH1A1MAPTANPEP
SCHEMBL25754504 0.83 HRH3 (0.31) LMNAHRH3
SCHEMBL25754478 0.78 LMNA (0.37) LMNAL3MBTL1MEN1KMT2AHRH3
SCHEMBL25754249 0.76 HRH3 (0.38) MEN1KMT2AHRH3ALDH1A1MAPT
SCHEMBL25754591 0.76 HRH3 (0.38) MEN1KMT2AHRH3ALDH1A1MAPT
SCHEMBL25754258 0.75 KDM4E (0.39) MEN1KMT2AHRH3ALDH1A1MAPT
SCHEMBL28879372 0.74 HRH3 (0.38) LMNAL3MBTL1MEN1KMT2AHRH3
SCHEMBL25754503 0.74 HRH3 (0.32) LMNAKMT2AHRH3ALDH1A1TSHR
SCHEMBL25754390 0.73 LMNA (0.35) LMNAL3MBTL1HRH3MAPTANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 LMNA 1517/4885L3MBTL1 480/4885MEN1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.