Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13549565 | 0.84 | TRPV1 (0.50) | FAAHTRPV1KIF11TDO2DGAT1 | |
| SCHEMBL12891149 | 0.79 | CYP1A2 (0.44) | FAAHTDO2ALDH1A1HPGDNPSR1 | |
| SCHEMBL8255870 | 0.79 | ASIC3 (0.53) | FAAHNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1011710 | 0.76 | FAAH (0.48) | FAAHTRPV1KIF11TDO2DGAT1 | |
| SCHEMBL1013500 | 0.76 | TRPV1 (0.45) | FAAHTRPV1KIF11TDO2DGAT1 | |
| SCHEMBL11785767 | 0.76 | ASIC3 (0.59) | FAAHTRPV1KIF11TDO2DGAT1 | |
| SCHEMBL2633158 | 0.74 | LOXL2 (0.46) | NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3721383 | 0.73 | FAAH (0.46) | FAAHTRPV1PDE2A | |
| SCHEMBL25243513 | 0.72 | ALDH1A1 (0.43) | FAAHTRPV1KIF11TDO2DGAT1 | |
| SCHEMBL30479919 | 0.72 | ALDH1A1 (0.43) | FAAHTRPV1KIF11TDO2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |