Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 2/20 | 0.30 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 3/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517117 | 0.87 | FFAR2 (0.30) | — | |
| SCHEMBL4517115 | 0.87 | FFAR2 (0.30) | — | |
| SCHEMBL2577892 | 0.84 | GPR119 (0.35) | NTRK1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL2588658 | 0.83 | NTRK1 (0.38) | NTRK1 | |
| SCHEMBL2584159 | 0.82 | DPP4 (0.36) | NTRK1ALDH1A1CHRM2CHRM1CHRM3 | |
| SCHEMBL2581259 | 0.82 | — | — | |
| SCHEMBL2588804 | 0.81 | RIPK1 (0.44) | NTRK1ALDH1A1JAK2 | |
| SCHEMBL2584042 | 0.81 | NTRK1 (0.45) | NTRK1JAK2 | |
| SCHEMBL2583332 | 0.81 | RIPK1 (0.37) | NTRK1CHRM2CHRM1CHRM3 | |
| SCHEMBL2581640 | 0.80 | FFAR2 (0.39) | NTRK1ALDH1A1JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |