Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2588658 | 0.92 | NTRK1 (0.38) | NTRK1GPR119 | |
| SCHEMBL2584159 | 0.89 | DPP4 (0.36) | NTRK1GPR119 | |
| SCHEMBL2577892 | 0.87 | GPR119 (0.35) | NTRK1GPR119 | |
| SCHEMBL4513904 | 0.86 | MEN1 (0.37) | NTRK1JAK2 | |
| SCHEMBL4513907 | 0.86 | MEN1 (0.37) | NTRK1JAK2 | |
| SCHEMBL2581640 | 0.85 | FFAR2 (0.39) | NTRK1GPR119JAK2 | |
| SCHEMBL2584569 | 0.85 | FFAR2 (0.39) | NTRK1GPR119JAK2 | |
| SCHEMBL2588804 | 0.84 | RIPK1 (0.44) | NTRK1GPR119JAK2 | |
| SCHEMBL2583332 | 0.83 | RIPK1 (0.37) | NTRK1 | |
| SCHEMBL2575487 | 0.81 | NTRK1 (0.32) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |